DNa12 [FBbt_00051200]

Sexually-dimorphic adult descending neuron with its soma in the anterior superior protocerebrum (McKellar et al., 2019; Sturner et al., 2025). It has arbors in many brain areas, including the anterior optic tubercle, subesophageal zone, inferior bridge, inferior and superior clamp, posterior ventrolateral, superior lateral and superior medial protocerebrum and superior posterior slope (McKellar et al., 2019). This arborization is predominantly ipsilateral, but one branch also crosses the midline in the supraesophageal ganglion (McKellar et al., 2019). It also innervates all ventral nerve cord neuromeres ipsilaterally (McKellar et al., 2019). The structure is quite similar in males and females, but there are some small differences in branching in the brain (McKellar et al., 2019). It innervates motor areas for the proboscis, legs and abdomen (McKellar et al., 2019). There is one of these cells per hemisphere and it elicits proboscis extension, more potently in males than females, and simultaneous movement of all legs (McKellar et al., 2019).
DNa12 DNa12 DNa12 DNa12

DNa12

ID: FBbt_00051200

Adult Nervous system Neuron

Sexually-dimorphic adult descending neuron with its soma in the anterior superior protocerebrum (McKellar et al., 2019; Sturner et al., 2025). It has arbors in many brain areas, including the anterior optic tubercle, subesophageal zone, inferior bridge, inferior and superior clamp, posterior ventrolateral, superior lateral and superior medial protocerebrum and superior posterior slope (McKellar et al., 2019). This arborization is predominantly ipsilateral, but one branch also crosses the midline in the supraesophageal ganglion (McKellar et al., 2019). It also innervates all ventral nerve cord neuromeres ipsilaterally (McKellar et al., 2019). The structure is quite similar in males and females, but there are some small differences in branching in the brain (McKellar et al., 2019). It innervates motor areas for the proboscis, legs and abdomen (McKellar et al., 2019). There is one of these cells per hemisphere and it elicits proboscis extension, more potently in males than females, and simultaneous movement of all legs (McKellar et al., 2019).

Open in VFB 3D Browser →
## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNxn004 exact synonym Stürner et al., 2025
DNa12 exact synonym Bates et al., 2025
DNa12 exact synonym Stürner et al., 2025
adult aSP22 descending neuron exact synonym Stürner et al., 2025
DNa12 exact synonym
DNa12 exact synonym Schlegel et al., 2024

Subclasses of DNa12 (2 total)

Thumbnail Name Tags
descending neuron of the anterior dorsal brain DNa12 (female) Adult, Nervous_system, Neuron
descending neuron of the anterior dorsal brain DNa12 (male) Adult, Nervous_system, Neuron

View all 2 results in VFB →

Expression patterns overlapping DNa12 (2 total)

View all 2 results in VFB →

Transgene expression in DNa12 (2 total)

View all 2 results in VFB →

Downstream connectivity classes for DNa12 (811 total)

Thumbnail Name Tags

View all 811 results in VFB →

Upstream connectivity classes for DNa12 (569 total)

Thumbnail Name Tags

View all 569 results in VFB →