DNg34 [FBbt_00047626]

Adult fruitless-expressing octopaminergic descending neuron of the DNg group, having a cell body near the midline of the anterior gnathal ganglion (Yu et al., 2010; Certel et al., 2010; Namiki et al., 2018), in the mandibular segment (Busch and Tanimoto, 2010). It forms bilaterally symmetric arbors in the ventromedial neuropils and the subesophageal zone (Busch et al., 2009; Namiki et al., 2018). It descends on the ipsilateral side of the cervical connective and fasciculates with the ventral lateral tract of the ventral cervical fascicle (Namiki et al., 2018). In the VNC, it innervates the T1, T2 and T3 leg neuropils and the abdominal neuromere, ipsilaterally (Busch et al., 2009; Namiki et al., 2018). There is one of these cells per hemisphere (Namiki et al., 2018). It is glutamatergic as well as octopaminergic (Cheong et al., 2024).
DNg34 DNg34 DNg34 DNg34

DNg34

ID: FBbt_00047626

Adult Glutamatergic Nervous system Octopaminergic

Adult fruitless-expressing octopaminergic descending neuron of the DNg group, having a cell body near the midline of the anterior gnathal ganglion (Yu et al., 2010; Certel et al., 2010; Namiki et al., 2018), in the mandibular segment (Busch and Tanimoto, 2010). It forms bilaterally symmetric arbors in the ventromedial neuropils and the subesophageal zone (Busch et al., 2009; Namiki et al., 2018). It descends on the ipsilateral side of the cervical connective and fasciculates with the ventral lateral tract of the ventral cervical fascicle (Namiki et al., 2018). In the VNC, it innervates the T1, T2 and T3 leg neuropils and the abdominal neuromere, ipsilaterally (Busch et al., 2009; Namiki et al., 2018). There is one of these cells per hemisphere (Namiki et al., 2018). It is glutamatergic as well as octopaminergic (Cheong et al., 2024).

Namiki et al. (2018), identified this as being morphologically similar to the octopaminergic VPM1 neuron (FBbt:00110149), described by Busch et al. (2009) (FBrf0207458) and the fruitless aDT8 neuron (FBbt:00110543), described by Yu et al. (2010) (FBrf0211884) - confirmed by Sturner et al. (2025) - FlyBase:FBrf0262850.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
fru-mcAL neuron broad synonym Yu et al., 2010
OA-VPM1 exact synonym Busch et al., 2009
DNg34 exact synonym Namiki et al., 2018
fru-aDT8 exact synonym Yu et al., 2010
DNxl010 exact synonym Stürner et al., 2025
DNg34 exact synonym Bates et al., 2025
adult fruitless aDT8 neuron exact synonym Yu et al., 2010
octopaminergic VPM1 neuron exact synonym Busch et al., 2009
DNg34 exact synonym doi_10_7554_eLife_97766_1
DNg34 exact synonym Berg et al., 2025
ventral paired median octopaminergic neuron 1 exact synonym Busch et al., 2009
DNg34 exact synonym Schlegel et al., 2024
fru-mcAL neuron broad synonym Lee et al., 2000
adult fruitless aDT8 neuron exact synonym Stürner et al., 2025
DNg34 exact synonym

List all available images of DNg34 (7 total)

Thumbnail Name Tags
DNg34_L (MaleCNS:10295) Nervous_system, Glutamatergic, Adult, Octopaminergic
DNg34_L (MaleCNS:10295) Nervous_system, Glutamatergic, Adult, Octopaminergic
DNg34_R (MaleCNS:13585) Nervous_system, Glutamatergic, Adult, Octopaminergic
TBD (MANC:10217) Nervous_system, Glutamatergic, GABAergic, Adult, Octopaminergic
TBD (MANC:10217) Nervous_system, Glutamatergic, GABAergic, Adult, Octopaminergic

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Expression patterns overlapping DNg34 (1 total)

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P{Tdc2-GAL4.C} expression pattern Expression_pattern

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Transgene expression in DNg34 (1 total)

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P{Tdc2-GAL4.C} expression pattern Expression_pattern

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Downstream connectivity classes for DNg34 (1516 total)

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Upstream connectivity classes for DNg34 (615 total)

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