DNp18 [FBbt_00047651]

Descending neuron belonging to the DNp group, having a cell body on the posterior surface of the brain, dorsal to the superior posterior slope (Matsuo et al., 2016; Namiki et al., 2018). The primary neurite extends anterioventrally and forms several branches at the medial side of the inferior posterior slope (Matsuo et al., 2016). The dorsal branch projects anterodorsally to form postsynaptic terminals in the epaulette and superior posterior slope (Matsuo et al., 2016). The anteriolateral and medial branches form postsynaptic terminals in the ipsilateral antennal mechanosensory and motor center zones B and E, respectively (Matsuo et al., 2016). The ventral branch extends posteroventrally to exit the brain, descending on the ipsilateral side of the cervical connective (Matsuo et al., 2016; Namiki et al., 2018). In the VNC, it fasciculates with the median tract of the dorsal cervical fascicle and innervates the neck and wing neuropils, intermediate tectulum, abdominal neuromere, and T2 and T3 leg neuropils (Namiki et al., 2018). It remains mainly ipsilateral, but some fibers may cross the midline in the VNC (Namiki et al., 2018). There is one of these cells per hemisphere (Namiki et al., 2018). It is cholinergic (Cheong et al., 2024).
DNp18 DNp18 DNp18 DNp18

DNp18

ID: FBbt_00047651

Adult Cholinergic Nervous system

Descending neuron belonging to the DNp group, having a cell body on the posterior surface of the brain, dorsal to the superior posterior slope (Matsuo et al., 2016; Namiki et al., 2018). The primary neurite extends anterioventrally and forms several branches at the medial side of the inferior posterior slope (Matsuo et al., 2016). The dorsal branch projects anterodorsally to form postsynaptic terminals in the epaulette and superior posterior slope (Matsuo et al., 2016). The anteriolateral and medial branches form postsynaptic terminals in the ipsilateral antennal mechanosensory and motor center zones B and E, respectively (Matsuo et al., 2016). The ventral branch extends posteroventrally to exit the brain, descending on the ipsilateral side of the cervical connective (Matsuo et al., 2016; Namiki et al., 2018). In the VNC, it fasciculates with the median tract of the dorsal cervical fascicle and innervates the neck and wing neuropils, intermediate tectulum, abdominal neuromere, and T2 and T3 leg neuropils (Namiki et al., 2018). It remains mainly ipsilateral, but some fibers may cross the midline in the VNC (Namiki et al., 2018). There is one of these cells per hemisphere (Namiki et al., 2018). It is cholinergic (Cheong et al., 2024).

Namiki et al. (2018), identify this as being morphologically similar to VGlut-F-200226 and fru-F-700251, described by FlyCircuit (FBrf0212704).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNp18 exact synonym Berg et al., 2025
DNp18 exact synonym Schlegel et al., 2024
DNp18 exact synonym Scheffer et al., 2020
DNp18 exact synonym
antennal mechanosensory and motor center AMMC Di3 neuron exact synonym Stürner et al., 2025
DNp18 exact synonym Namiki et al., 2018
antennal mechanosensory and motor center AMMC Di3 neuron exact synonym Matsuo et al., 2016
DNp18 exact synonym doi_10_7554_eLife_97766_1
DNp18 exact synonym Bates et al., 2025
DNxn033 exact synonym Stürner et al., 2025
AMMC-Di3 exact synonym Matsuo et al., 2016

List all available images of DNp18 (12 total)

Thumbnail Name Tags
DNp18_L (MaleCNS:10048) Nervous_system, Adult, Cholinergic
DNp18_L (MaleCNS:10048) Nervous_system, Adult, Cholinergic
DNp18_R (MaleCNS:10026) Nervous_system, Adult, Cholinergic
DNp18_R (MaleCNS:10026) Nervous_system, Adult, Cholinergic
TBD (MANC:10021) Nervous_system, Adult, Cholinergic

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Expression patterns overlapping DNp18 (4 total)

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Transgene expression in DNp18 (4 total)

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Downstream connectivity classes for DNp18 (461 total)

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Upstream connectivity classes for DNp18 (347 total)

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